Motif ID: FOX{I1,J2}.p2

Z-value: 1.550


Transcription factors associated with FOX{I1,J2}.p2:

Gene SymbolEntrez IDGene Name
Foxi1 14233 forkhead box I1
Foxj2 60611 forkhead box J2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxj2chr6_+_1227702010.368.4e-07Click!
Foxi1chr11_-_341080530.199.3e-03Click!


Activity profile for motif FOX{I1,J2}.p2.

activity profile for motif FOX{I1,J2}.p2


Sorted Z-values histogram for motif FOX{I1,J2}.p2

Sorted Z-values for motif FOX{I1,J2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{I1,J2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_32557916 64.362 NM_021319
Pglyrp2
peptidoglycan recognition protein 2
chr17_-_32557807 59.379 Pglyrp2
peptidoglycan recognition protein 2
chr15_+_103284200 37.257 NM_153505
Nckap1l
NCK associated protein 1 like
chr10_-_61960613 31.104 Srgn
serglycin
chr15_+_83393975 28.805 NM_009775
Tspo
translocator protein
chr2_-_27118325 28.310 Vav2
vav 2 oncogene
chr6_-_48658211 28.282 NM_153175
Gimap6
GTPase, IMAP family member 6
chr18_-_35900005 24.786 NM_028261
Tmem173
transmembrane protein 173
chr2_+_24242134 24.700 Psd4
pleckstrin and Sec7 domain containing 4
chr12_-_80084464 24.197 NM_001170401
Tmem229b
transmembrane protein 229B
chr14_-_56407622 23.882 NM_001164107
NM_001164108
NM_019955
Ripk3


receptor-interacting serine-threonine kinase 3


chr12_-_27141303 23.575 NM_021384
Rsad2
radical S-adenosyl methionine domain containing 2
chr13_-_56280161 23.033 NM_001168615
NM_145976
Tifab

TRAF-interacting protein with forkhead-associated domain, family member B

chr5_+_86500770 22.756 NM_019992
Stap1
signal transducing adaptor family member 1
chr11_+_87569075 21.941 A430104N18Rik
RIKEN cDNA A430104N18 gene
chr5_-_73127743 21.538 NM_013698
Txk
TXK tyrosine kinase
chr17_+_34442837 21.292 H2-Eb1
histocompatibility 2, class II antigen E beta
chr7_+_134439804 20.348 NM_008400
Itgal
integrin alpha L
chr6_-_48658182 20.286 Gimap6
GTPase, IMAP family member 6
chr1_+_173847645 19.462 NM_030710
Slamf6
SLAM family member 6
chr11_+_82988687 19.353 NM_011410
Slfn4
schlafen 4
chr11_+_106612525 19.308 NM_001033435
Gm885
predicted gene 885
chr2_-_3283840 19.280 NM_145921
Olah
oleoyl-ACP hydrolase
chr19_-_41289262 18.952 Tm9sf3
transmembrane 9 superfamily member 3
chr5_-_65351226 18.458 NM_011604
Tlr6
toll-like receptor 6
chr1_-_55044032 18.380 Sf3b1
splicing factor 3b, subunit 1
chr5_+_115373246 17.877 NM_145209
Oasl1
2'-5' oligoadenylate synthetase-like 1
chr15_-_103085703 17.790 NM_008685
Nfe2
nuclear factor, erythroid derived 2
chr17_+_37407160 17.607 NM_013819
H2-M3
histocompatibility 2, M region locus 3
chr8_-_124948837 17.325


chr12_-_27141277 17.272 Rsad2
radical S-adenosyl methionine domain containing 2
chr2_-_148263617 17.180 Cd93
CD93 antigen
chr3_-_58905678 17.040 NM_173398
Gpr171
G protein-coupled receptor 171
chr17_+_34442808 16.888 NM_010382
H2-Eb1
histocompatibility 2, class II antigen E beta
chr14_+_78304045 16.825 NM_029495
NM_178825
Epsti1

epithelial stromal interaction 1 (breast)

chr19_+_3935169 16.510 NM_001161428
NM_019449
Unc93b1

unc-93 homolog B1 (C. elegans)

chr6_-_122560002 16.225 Gdf3
growth differentiation factor 3
chr19_+_36453556 16.209 NM_029508
Pcgf5
polycomb group ring finger 5
chr17_+_6910178 16.145 NM_183368
Sytl3
synaptotagmin-like 3
chr17_+_48594225 16.103 NM_152823
Unc5cl
unc-5 homolog C (C. elegans)-like
chr6_-_122560022 15.907 NM_008108
Gdf3
growth differentiation factor 3
chr11_-_83388330 15.498 Ccl9
chemokine (C-C motif) ligand 9
chr16_-_4679664 15.348 NM_030205
Coro7
coronin 7
chr4_+_125806078 15.300 Stk40
serine/threonine kinase 40
chr11_+_58680717 15.262 NM_172403
2810021J22Rik
RIKEN cDNA 2810021J22 gene
chr1_+_155596555 14.797 NM_011882
Rnasel
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr6_+_54839147 14.772 Znrf2
zinc and ring finger 2
chr7_-_148452299 14.625 NM_016850
Irf7
interferon regulatory factor 7
chr8_+_90812964 14.555 NM_001037723
Adcy7
adenylate cyclase 7
chr2_-_26314921 14.187 Notch1
Notch gene homolog 1 (Drosophila)
chr14_+_79915429 14.017 Elf1
E74-like factor 1
chr6_+_48689045 13.707 NM_008376
NM_175860
Gimap1

GTPase, IMAP family member 1

chr19_+_29441927 13.428 NM_021893
Cd274
CD274 antigen
chr10_-_18731766 13.365 NM_001166402
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr19_+_12535536 13.265 Mpeg1
macrophage expressed gene 1
chr17_+_5343877 13.164 Arid1b
AT rich interactive domain 1B (SWI-like)
chr10_+_75052084 13.119 NM_011820
Ggt5
gamma-glutamyltransferase 5
chr5_-_134705423 12.922 NM_010876
Ncf1
neutrophil cytosolic factor 1
chr7_+_73205419 12.736 Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr9_+_21142267 12.695 NM_152808
Slc44a2
solute carrier family 44, member 2
chr5_+_145888588 12.551 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr15_+_102289600 12.305 NM_001170911
NM_025385
Prr13

proline rich 13

chr2_+_163899842 12.239 NM_021420
Stk4
serine/threonine kinase 4
chr1_+_132762248 12.223 Faim3
Fas apoptotic inhibitory molecule 3
chr3_+_109376824 12.078 NM_146139
Vav3
vav 3 oncogene
chr8_-_131589372 12.023 NM_001197041
NM_029061
Ccdc7

coiled-coil domain containing 7

chr7_-_113358823 11.892 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr7_-_113102453 11.892 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr19_+_12535268 11.871 NM_010821
Mpeg1
macrophage expressed gene 1
chr9_-_96378951 11.640 NM_011279
Rnf7
ring finger protein 7
chr17_+_35189798 11.602


chr5_+_104754347 11.589 NM_053172
Mepe
matrix extracellular phosphoglycoprotein with ASARM motif (bone)
chr8_+_77972592 11.544 NM_001164235
NM_027944
1700007B14Rik

RIKEN cDNA 1700007B14 gene

chr13_-_51829951 11.512 Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr5_+_115373272 11.294 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr5_+_136559785 11.240 NM_001039103
NM_133914
Rasa4

RAS p21 protein activator 4

chr10_+_127936302 11.225 A430046D13Rik
Riken cDNA A430046D13 gene
chr6_+_67966702 11.093


chr9_-_7872896 11.087 NM_007464
Birc3
baculoviral IAP repeat-containing 3
chr19_-_60302398 10.935 D19Ertd737e
DNA segment, Chr 19, ERATO Doi 737, expressed
chr13_+_52692221 10.926 NM_011518
Sykb
spleen tyrosine kinase
chr7_+_73205454 10.606 Snrpa1
small nuclear ribonucleoprotein polypeptide A'
chr8_+_35178083 10.348 NM_001126314
Mboat4
membrane bound O-acyltransferase domain containing 4
chr9_-_71011053 10.308 NM_022026
Aqp9
aquaporin 9
chr13_+_27248667 10.286 NM_172156
Prl3d3
prolactin family 3, subfamily d, member 3
chr16_-_94509462 9.940 NM_139145
Hlcs
holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase)
chr13_-_97804287 9.914 NM_001080777
NM_025585
1700029F12Rik

RIKEN cDNA 1700029F12 gene

chr17_+_35403998 9.900


chr3_-_15426426 9.799 NM_001002898
Sirpb1a
signal-regulatory protein beta 1A
chr1_+_74200562 9.792 NM_009909
Cxcr2
chemokine (C-X-C motif) receptor 2
chr19_+_37624879 9.711 NM_175353
Exoc6
exocyst complex component 6
chr10_+_126504125 9.641


chr11_+_61466766 9.614 Grap
GRB2-related adaptor protein
chr4_-_6381171 9.609 Nsmaf
neutral sphingomyelinase (N-SMase) activation associated factor
chr5_+_38651466 9.605 NM_025480
Tmem128
transmembrane protein 128
chr5_-_31950177 9.579 Rbks
ribokinase
chr8_+_131591033 9.574 NM_001168369
NM_029292
1700008F21Rik

RIKEN cDNA 1700008F21 gene

chr1_-_146024404 9.523 NM_153171
Rgs13
regulator of G-protein signaling 13
chr9_-_32348863 9.481 NM_008026
Fli1
Friend leukemia integration 1
chr7_-_48755259 9.424 NM_001033530
AW146154
expressed sequence AW146154
chr9_+_114640266 9.413 NM_026036
Cmtm6
CKLF-like MARVEL transmembrane domain containing 6
chr11_-_46202942 9.366 NM_010583
Itk
IL2-inducible T-cell kinase
chr11_-_98190774 9.234 NM_010895
Neurod2
neurogenic differentiation 2
chr3_-_15748418 9.126 NM_001173459
LOC100038947
Sirpb1a
signal-regulatory protein beta 1-like
signal-regulatory protein beta 1A
chr10_-_111434265 9.096 NM_028608
Glipr1
GLI pathogenesis-related 1 (glioma)
chr17_-_34133397 9.036 H2-K1
histocompatibility 2, K1, K region
chr15_-_9459612 8.995 NM_008372
Il7r
interleukin 7 receptor
chr3_-_144347983 8.992


chr11_+_61466797 8.991 NM_027817
Grap
GRB2-related adaptor protein
chr5_+_114580397 8.988 NM_001040691
Ung
uracil DNA glycosylase
chr5_+_106039499 8.936 Lrrc8c
leucine rich repeat containing 8 family, member C
chr10_-_111434231 8.926 Glipr1
GLI pathogenesis-related 1 (glioma)
chr19_-_44210311 8.867 NM_001081077
Cwf19l1
CWF19-like 1, cell cycle control (S. pombe)
chr1_+_133535033 8.848 Ctse
cathepsin E
chr6_-_129225348 8.690 NM_001033122
Cd69
CD69 antigen
chr19_-_27463532 8.675


chr4_+_128688217 8.605


chr7_-_34977928 8.506 Pdcd2l
programmed cell death 2-like
chr19_-_30623890 8.505 NM_010051
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr19_+_12873115 8.494 Lpxn
leupaxin
chr8_+_23348971 8.453 NM_019576
Thsd1
thrombospondin, type I, domain 1
chr2_+_153956082 8.345 NM_028528
1700058C13Rik
RIKEN cDNA 1700058C13 gene
chr6_+_100783598 8.336 NM_182939
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chr17_+_87316687 8.313 NM_030104
1700090G07Rik
RIKEN cDNA 1700090G07 gene
chr6_-_129572590 8.308 NM_033078
Klrk1
killer cell lectin-like receptor subfamily K, member 1
chr14_+_27813547 8.302 NM_010420
Hesx1
homeobox gene expressed in ES cells
chr19_+_12873063 8.297 NM_134152
Lpxn
leupaxin
chr9_+_123715592 8.261 NM_030712
Cxcr6
chemokine (C-X-C motif) receptor 6
chr17_+_33102747 8.208 NM_153063
Zfp472
zinc finger protein 472
chr5_+_115346942 8.205 NM_011854
Oasl2
2'-5' oligoadenylate synthetase-like 2
chr4_-_149072755 8.184 NM_001164049
NM_001164050
NM_008840
Pik3cd


phosphatidylinositol 3-kinase catalytic delta polypeptide


chr3_-_106592919 8.144 NM_007651
Cd53
CD53 antigen
chr1_+_109407998 8.143 NM_001174170
NM_011111
Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

chr9_+_38525852 8.121 NM_001145957
NM_172767
Vwa5a

von Willebrand factor A domain containing 5A

chrX_-_162948399 8.088 NM_001007577
Tceanc
transcription elongation factor A (SII) N-terminal and central domain containing
chr13_-_64230610 8.069 NM_001001321
Slc35d2
solute carrier family 35, member D2
chrX_-_7544940 8.066 NM_008089
Gata1
GATA binding protein 1
chrX_-_154006916 8.062 NM_001098723
Yy2
Mbtps2
Yy2 transcription factor
membrane-bound transcription factor peptidase, site 2
chr9_-_62644026 8.009 Fem1b
feminization 1 homolog b (C. elegans)
chr7_-_25873560 7.965


chr2_-_164182009 7.964 Slpi
secretory leukocyte peptidase inhibitor
chr4_-_149075697 7.867 NM_001029837
Pik3cd
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr2_+_32583221 7.839 Sh2d3c
SH2 domain containing 3C
chr11_+_53164267 7.794 NM_033565
Aff4
AF4/FMR2 family, member 4
chr12_+_75028976 7.783 Hif1a
hypoxia inducible factor 1, alpha subunit
chr7_-_16807341 7.781 NM_027883
Dhx34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr16_+_44811858 7.657 Cd200r4
CD200 receptor 4
chr6_-_118089060 7.603 NM_030165
Csgalnact2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr2_-_118554094 7.581 NM_177568
Plcb2
phospholipase C, beta 2
chr16_+_59471600 7.548 NM_025910
Mina
myc induced nuclear antigen
chr11_-_99855307 7.464 NM_001099774
Krtap17-1
keratin associated protein 17-1
chr1_+_52687548 7.396 NM_001142647
Tmem194b
transmembrane protein 194B
chr9_+_43552516 7.394 NM_021424
Pvrl1
poliovirus receptor-related 1
chr7_+_134439888 7.345 Itgal
integrin alpha L
chrX_+_156411885 7.340 Sh3kbp1
SH3-domain kinase binding protein 1
chr17_+_37006518 7.326 NM_011280
Trim10
tripartite motif-containing 10
chr2_-_91019477 7.312 NM_001177720
Madd
MAP-kinase activating death domain
chr13_+_95335701 7.274


chr1_-_80661844 7.256 Dock10
dedicator of cytokinesis 10
chr12_+_72149332 7.252 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr9_-_88626434 7.197 Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr16_+_91465283 7.173 A930006K02Rik
RIKEN cDNA A930006K02 gene
chr2_-_60589953 7.172 Rbms1
RNA binding motif, single stranded interacting protein 1
chr5_-_65323937 7.172 NM_030682
Tlr1
toll-like receptor 1
chr13_-_53472732 7.166 Sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr6_+_83293025 7.145 Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr14_+_21520038 7.090


chr1_-_173579128 7.044 Slamf7
SLAM family member 7
chr6_-_115685120 7.044 NM_001168258
Tmem40
transmembrane protein 40
chr9_-_14185399 6.985 Endod1
endonuclease domain containing 1
chr2_-_154196611 6.970 Cdk5rap1
CDK5 regulatory subunit associated protein 1
chr1_+_161974815 6.968 4930523C07Rik
RIKEN cDNA 4930523C07 gene
chrX_+_70437517 6.945 NM_001081643
Xlr3b
X-linked lymphocyte-regulated 3B
chr17_+_22498419 6.944 NM_145484
Zfp758
zinc finger protein 758
chr3_+_95466898 6.918


chr18_-_32719516 6.890 NM_001048207
Gypc
glycophorin C
chr10_+_96079634 6.864 NM_007569
Btg1
B-cell translocation gene 1, anti-proliferative
chr1_-_173579057 6.863 Slamf7
SLAM family member 7
chr6_+_83065466 6.833 NM_020619
Mogs
mannosyl-oligosaccharide glucosidase
chr1_+_132762353 6.830 NM_026976
Faim3
Fas apoptotic inhibitory molecule 3
chr6_+_53523365 6.816 NM_172728
Creb5
cAMP responsive element binding protein 5
chr5_+_137170046 6.808 NM_001085387
Myl10
myosin, light chain 10, regulatory
chr17_-_50329593 6.720 NM_181397
Rftn1
raftlin lipid raft linker 1
chr17_-_51878720 6.709 Satb1
special AT-rich sequence binding protein 1
chr2_+_132516018 6.697 NM_028637
1110034G24Rik
RIKEN cDNA 1110034G24 gene
chr12_+_82049290 6.691 Srsf5
serine/arginine-rich splicing factor 5
chr9_-_14185685 6.684 NM_028013
Endod1
endonuclease domain containing 1
chr1_-_173537404 6.682 NM_008534
Ly9
lymphocyte antigen 9
chr13_-_53472719 6.632 NM_009269
Sptlc1
serine palmitoyltransferase, long chain base subunit 1
chr19_-_41289045 6.593 Tm9sf3
transmembrane 9 superfamily member 3
chr9_+_7792286 6.566 Tmem123
transmembrane protein 123
chr17_+_35404109 6.566


chr4_+_134483092 6.555


chr9_-_71743854 6.532 Tcf12
transcription factor 12
chrX_+_104284572 6.517 NM_172435
P2ry10
purinergic receptor P2Y, G-protein coupled 10
chr9_-_21767872 6.493 NM_010149
Epor
erythropoietin receptor
chr4_-_43666412 6.477 NM_001007463
Spag8
sperm associated antigen 8
chr17_+_28667805 6.474 NM_026290
4930511I11Rik
RIKEN cDNA 4930511I11 gene
chr5_+_30969259 6.423 NM_007681
Cenpa
centromere protein A
chr6_-_52190771 6.403 NM_001122950
Hoxa10
homeobox A10

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.24 9.85e-06 GO:0019222 regulation of metabolic process
1.29 3.02e-05 GO:0009889 regulation of biosynthetic process
1.32 4.97e-05 GO:0006355 regulation of transcription, DNA-dependent
1.29 6.80e-05 GO:0010468 regulation of gene expression
1.28 7.47e-05 GO:0031326 regulation of cellular biosynthetic process
1.24 1.30e-04 GO:0080090 regulation of primary metabolic process
1.30 1.45e-04 GO:0051252 regulation of RNA metabolic process
1.29 1.59e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.23 3.52e-04 GO:0060255 regulation of macromolecule metabolic process
1.28 4.43e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.26 4.46e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.27 5.13e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.22 7.95e-04 GO:0006807 nitrogen compound metabolic process
1.34 9.47e-04 GO:0006351 transcription, DNA-dependent
1.27 1.04e-03 GO:0010467 gene expression
1.33 1.11e-03 GO:0032774 RNA biosynthetic process
1.22 1.44e-03 GO:0031323 regulation of cellular metabolic process
1.28 1.81e-03 GO:0016070 RNA metabolic process
1.46 2.32e-03 GO:0002376 immune system process
1.22 2.76e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 3.97e-03 GO:0090304 nucleic acid metabolic process
1.21 4.91e-03 GO:0034641 cellular nitrogen compound metabolic process
1.61 2.18e-02 GO:0080134 regulation of response to stress
1.14 4.83e-02 GO:0043170 macromolecule metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.22 7.23e-08 GO:0005634 nucleus
1.38 2.59e-06 GO:0044428 nuclear part
1.41 5.27e-06 GO:0031981 nuclear lumen
1.34 1.21e-04 GO:0070013 intracellular organelle lumen
1.34 1.41e-04 GO:0043233 organelle lumen
1.33 2.51e-04 GO:0031974 membrane-enclosed lumen
1.71 8.17e-04 GO:0005730 nucleolus
1.45 1.16e-02 GO:0044451 nucleoplasm part
1.35 2.09e-02 GO:0005654 nucleoplasm

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.09 1.86e-04 GO:0005488 binding
1.25 9.31e-04 GO:0003676 nucleic acid binding
1.45 1.01e-03 GO:0030528 transcription regulator activity
1.29 3.36e-03 GO:0003677 DNA binding
2.47 2.07e-02 GO:0008026 ATP-dependent helicase activity
2.47 2.07e-02 GO:0070035 purine NTP-dependent helicase activity
1.40 4.14e-02 GO:0001071 nucleic acid binding transcription factor activity
1.40 4.14e-02 GO:0003700 sequence-specific DNA binding transcription factor activity